Table 1.
Area under the curve (AUC) values from choline efflux experiments.
Data | Condition | AUC value1 | N |
---|---|---|---|
Figs. 1-2 | NMDA | 2000 ± 415 | 16 |
Fig. 1A | NMDA/50% chloride | 870 ± 282a | 4 |
NMDA/Low chloride | 323 ± 59a | 4 | |
NMDA/Zero chloride | 363 ± 158a | 4 | |
Fig. 1B | NMDA + Bicuculline | 1532 ± 227b | 6 |
Bicuculline alone | 335 ± 166c | 6 | |
Controls | 119 ± 90b | 6 | |
Fig. 2 | NMDA + GABA | 1844 ± 656 | 4 |
NMDA + Bilobalide | 146 ± 149a | 5 | |
NMDA + Bilo + GABA | 1063 ± 184a | 4 | |
GABA alone | 370 ± 128c | 4 |
AUC values were calculated from the data shown in Figs. 1 and 2, for 30 minutes of choline release. They are given as arbitrary units (AU, formally representing [%] · min) normalized to 2000 AU for NMDA effects from different experiments (absolute values for NMDA-induced choline releases were between 1200 and 2500 AU in individual experiments). Statistical evaluation (ANOVA with Dunnett post-test):
p<0.01 vs. NMDA.
p<0.05 vs. NMDA.
p<0.05 vs. controls.