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. Author manuscript; available in PMC: 2007 May 3.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2007 Mar 15;67(4):1179–1186. doi: 10.1016/j.ijrobp.2006.11.037

Figure 4. Tumor growth with respect to irradiation.

Figure 4

Mean interpolated volume ± SE as a function of time, with each tumor normalized to its initial size at irradiation (Day 0).

A: For large AT1 tumors, no significant growth delay (α =0.05) was observed for tumors on oxygen breathing rats (solid) as compared to air breathing (dotted). Dashed line shows predicted growth of control tumors.

B: For small AT1 tumors, oxygen inhalation during irradiation (solid) resulted in a statistically significant (p<0.001) growth delay, which was evident by day 13 compared with air breathing rats (dotted). Both groups also showed significant delay compared with non-irradiated controls by day 7.