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. 2006 Nov 13;360(1):36–49. doi: 10.1016/j.virol.2006.10.026

Table 2.

Anti-VSVIN serum neutralization antibodies

Study Route Group Day Geometric mean titera
Shedding IN rVSVIN 8 < 40
14 1040
22 1890
Control 22 < 40
Neuroinvasiveness IN wt VSVIN 21 1522
rVSVIN 21 2167
rVSVIN-HIVGag5 21 1280
rVSVIN–CT1-HIVGag5 21 < 40
PBS 21 < 40
Neurovirulence IT wt VSVIN 8 226
rVSVIN 8b 40
21c 1280
rVSVIN-HIVGag5 21 4305
rVSVIN-CT1-HIVGag5 21 80
PBS 21 < 40
a

Titer expressed as reciprocal dilution required to neutralize 100 PFU VSV (limit of detection = 40).

b

One macaque in this group was euthanized by day 8.

c

Three macaques in this group survived 21 days.