Table 2.

Inclusion and exclusion criteria of DIAMOND

1. Patients are included when they visit their GP for complaints of which the GP thinks that they originate from the upper GI tract and for which acid-suppressive medication can be effective.

2. Patients are included when they are 18 years or older.

3. Patients are excluded when they have used prescribed acid-suppressive medication in the last 3 months before inclusion.

4. Patients are excluded when they have had a gastroscopy in the year prior to inclusion.

5. Patients are excluded when they have alarming symptoms.

6. Patients are excluded when there are contraindications for prescribing acid-suppressive medication, such as pregnancy, liver or kidney malfunction.

7. Patients are excluded when they are not able to fill out (Dutch) questionnaires, for example because of language problems.