Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 May 16;2(5):e450. doi: 10.1371/journal.pone.0000450

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

Skeleton preparations from 6-week-old R26^floxneoWnt4; Col2a1-Cre mutants and R26^floxneoWnt4controls. A, Intact skeletons, control (left) and mutant (right). B, Dorsal view of skulls, control (left) and mutant (right). C, individual dorsal skull bones, control (left) and mutant (right). D, Isolated forelimbs, mutant (top) and control (bottom). E, Isolated hindlimbs, mutant (top) and control (bottom). F, Third lumbar vertebrae, showing lateral ossifications (arrow) in the control (left) that are hypoplastic in the mutant (right). G, Isolated pelvic bones from 6-week-old mice, control (left) and mutant (right). H, Higher magnification of boxed region shown in panel G, showing pubic and ischial bone fusion of the control. I, Higher magnification of boxed region shown in panel G, showing lack of fusion between the pubic and ischial bones of the mutant. fr, frontal bone; nas, nasal bone; par, parietal bone; oc, occipital bone.