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Assembly of 6-deoxyerythronolide B (6-DEB), the aglycone of erythromycin, on a type I modular polyketide synthase. (AT = adenyltransferase, KS = ketosynthase, ACP = acyl carrier protein, KR = ketoreductase, DH = dehydratase, ER = enoate reductase, TE = thioesterase).
