Table 1.

Sequences and activities of selected α-conotoxins

Name	Spacinga	Sequence	Receptorb	Species	Ref.
GI	3/5	ECC-NPACGRHYSC*	M α1β1γδ	C. geographus	[13]
ImI	4/3	GCCSDPRCAWRC*	N α7	C. imperialis	[41]
BuIA	4/4	GCCSTPPCAVLYC*	N α6/α3 β4/β2	C. bullatus	[16]
AuIB	4/6	GCCSYPPCFATNPDC*	N α3 β4	C. aulicus	[42]
PnIA	4/7	GCCSLPPCAANNPDYC*	N α3 β2	C. pennaceus	[43]
Cys	I	II	III	IV

^a number of residues between the second and third, and the third and fourth cysteines

^b M, muscle nAChR; N, neuronal nAChR

* C terminal amide

Sequences, in one letter code, are aligned using the conserved cysteines forming disulfide bonds, shown in bold.