Table 2.
Diagnostic Group | 1996–2002 | 1998–2000 | ||||||||||||||||||||
CHIS | MC | GRO | MS | MOR | JAL | NL | PUE | VER | YUC | Overall | ||||||||||||
n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | |
I. Leukemias | 54 | 37.8 | 321 | 43.7 | 43 | 34.4 | 431 | 51.4 | 54 | 46.2 | 97 | 50.8 | 56 | 31.6 | 56 | 49.1 | 60 | 48.0 | 25 | 49.0 | 1197 | 45.81 |
+ Acute lymphoblastic | 37 | 68.5 | 249 | 77.6 | 35 | 81.4 | 352 | 81.7 | 42 | 77.7 | 78 | 80.3 | 53 | 94.6 | 48 | 85.7 | 46 | 76.7 | 18 | 72.0 | 958 | 80.02 |
+ Acute non-lymphoblastic | 16 | 29.6 | 58 | 18.1 | 7 | 16.3 | 70 | 16.3 | 12 | 22.3 | 16 | 16.5 | 3 | 5.4 | 8 | 14.3 | 11 | 18.3 | 5 | 20.0 | 206 | 17.2 |
II. Lymphomas3 | 15 | 10.5 | 88 | 12.0 | 21 | 16.8 | 75 | 9.0 | 15 | 12.9 | 17 | 8.9 | 22 | 12.4 | 19 | 16.7 | 16 | 12.8 | 1 | 2.0 | 289 | 11.1 |
+ Hodgkin lymphomas | 6 | 40.0 | 23 | 25.9 | 7 | 33.3 | 36 | 47.8 | 3 | 20.2 | 6 | 34.8 | 10 | 45.2 | 10 | 52.7 | 9 | 56.3 | 1 | 100.0 | 111 | 38.4 |
+ Non Hodgkin lymphomas | 7 | 46.7 | 53 | 60.4 | 9 | 42.9 | 35 | 46.7 | 9 | 59.7 | 7 | 41.6 | 8 | 36.3 | 8 | 41.9 | 4 | 25.0 | 0 | 0.0 | 140 | 48.4 |
+ Burkitt lymphoma | 2 | 13.3 | 9 | 10.3 | 5 | 23.8 | 3 | 4.4 | 3 | 20.2 | 4 | 23.6 | 3 | 13.7 | 1 | 5.4 | 3 | 18.8 | 0 | 0.0 | 33 | 11.4 |
III. CNS tumors | 21 | 14.7 | 98 | 13.4 | 23 | 18.4 | 75 | 9.0 | 11 | 9.5 | 20 | 10.5 | 33 | 18.6 | 10 | 8.8 | 19 | 15.2 | 5 | 9.8 | 315 | 12.0 |
+ Ependymomas | 3 | 14.3 | 14 | 14.2 | 3 | 13.0 | 10 | 13.3 | 1 | 9.5 | 1 | 4.9 | 2 | 5.9 | 0 | 0.0 | 4 | 21.1 | 0 | 0.0 | 38 | 12.1 |
+ Astrocytomas | 9 | 42.9 | 52 | 53.0 | 13 | 56.5 | 31 | 41.1 | 5 | 45.3 | 5 | 24.8 | 14 | 42.5 | 4 | 39.8 | 5 | 26.3 | 1 | 20.4 | 139 | 44.1 |
+ IIET | 5 | 23.8 | 25 | 25.4 | 6 | 26.1 | 25 | 33.3 | 3 | 27.4 | 4 | 20.3 | 12 | 36.6 | 1 | 10.2 | 5 | 26.3 | 2 | 39.8 | 88 | 27.9 |
IV. Neuroblastoma and others | 3 | 2.1 | 22 | 3.0 | 8 | 6.4 | 16 | 1.9 | 2 | 1.7 | 4 | 2.1 | 11 | 6.2 | 1 | 0.9 | 1 | 0.8 | 3 | 5.9 | 71 | 2.7 |
+ Neuroblastoma | 3 | 100.0 | 21 | 96.7 | 8 | 100.0 | 14 | 89.5 | 2 | 100.0 | 4 | 100.0 | 10 | 90.3 | 1 | 100.0 | 1 | 100.0 | 3 | 100.0 | 66 | 93.0 |
V. Retinoblastoma | 12 | 8.4 | 26 | 3.5 | 5 | 4.0 | 33 | 3.9 | 6 | 5.1 | 3 | 1.6 | 7 | 4.0 | 4 | 3.5 | 6 | 4.8 | 3 | 5.9 | 105 | 4.0 |
VI. Renal tumors | 4 | 2.8 | 30 | 4.1 | 7 | 5.6 | 33 | 4.0 | 7 | 6.0 | 5 | 2.6 | 10 | 5.6 | 2 | 1.8 | 6 | 4.8 | 2 | 3.9 | 106 | 4.1 |
+ Nephroblastoma | 4 | 100.0 | 28 | 97.5 | 7 | 100.0 | 33 | 100.0 | 7 | 100.0 | 5 | 100.0 | 10 | 100.0 | 2 | 100.0 | 6 | 100.0 | 2 | 100.0 | 105 | 99.1 |
VII. Hepatic tumors | 3 | 2.1 | 19 | 2.6 | 0 | 0.0 | 10 | 1.2 | 1 | 0.9 | 4 | 2.1 | 3 | 1.7 | 6 | 5.3 | 1 | 0.8 | 1 | 2.0 | 48 | 1.8 |
+ Hepatoblastoma | 2 | 66.7 | 17 | 88.5 | 0 | 0.0 | 9 | 91.7 | 1 | 100.0 | 4 | 100.0 | 3 | 100.0 | 6 | 100.0 | 1 | 100.0 | 1 | 100.0 | 44 | 91.7 |
VIII. Bone tumors | 10 | 7.0 | 39 | 5.3 | 8 | 6.4 | 47 | 5.6 | 7 | 6.0 | 20 | 10.5 | 5 | 2.8 | 5 | 4.4 | 3 | 2.4 | 4 | 7.8 | 148 | 5.7 |
+ Osteosarcomas | 8 | 80.0 | 27 | 70.0 | 5 | 62.5 | 36 | 76.8 | 4 | 56.7 | 19 | 94.9 | 4 | 80.0 | 3 | 59.1 | 2 | 66.7 | 2 | 50.0 | 110 | 74.3 |
IX. Soft tissue sarcomas | 9 | 6.3 | 41 | 5.6 | 6 | 4.8 | 44 | 5.3 | 7 | 6.0 | 13 | 6.8 | 14 | 7.9 | 5 | 4.4 | 4 | 3.2 | 2 | 3.9 | 145 | 5.5 |
+ Rhabdomyosarcomas | 4 | 44.4 | 25 | 61.2 | 1 | 16.7 | 27 | 60.4 | 4 | 56.7 | 8 | 61.8 | 12 | 85.4 | 2 | 40.9 | 4 | 100.0 | 1 | 50.0 | 88 | 60.7 |
+ Fibrosarcomas | 4 | 44.4 | 9 | 21.9 | 1 | 16.7 | 8 | 18.9 | 1 | 15.0 | 0 | 0.0 | 1 | 7.3 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 24 | 16.6 |
X. Germ cell tumors | 7 | 4.9 | 45 | 6.1 | 2 | 1.6 | 67 | 8.0 | 5 | 4.3 | 7 | 3.7 | 14 | 7.9 | 6 | 5.3 | 9 | 7.2 | 5 | 9.8 | 167 | 6.4 |
+ Malignant gonadal | 4 | 57.1 | 35 | 77.8 | 2 | 100.0 | 49 | 72.5 | 2 | 39.5 | 3 | 43.2 | 10 | 70.9 | 4 | 66.0 | 4 | 44.4 | 4 | 79.6 | 117 | 70.1 |
XI. Carcinomas | 5 | 3.5 | 5 | 0.7 | 2 | 1.6 | 7 | 0.7 | 2 | 1.7 | 1 | 0.5 | 2 | 1.1 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 24 | 0.9 |
TOTAL | 143 | 100 | 734 | 100 | 125 | 100 | 838 | 100 | 117 | 100 | 191 | 100 | 177 | 100 | 114 | 100 | 125 | 100 | 51 | 100 | 2615 | 100 |
1Intergroup frequency (%); 2Intragroup frequency (%), only the frequencies of principal subgroups are presented; 363 cases of Histiocytosis were not included; IMSS, Instituto Mexicano del Seguro Social; n, Number of cases; CNS, Central Nervous System; IIET, Intracraneal and Intraespinal Embryonal Tumors; CHIS, Chiapas; MC, Mexico City; GRO, Guerrero; MS, Mexico State; MOR, Morelos; JAL, Jalisco; NL, Nuevo León; PUE, Puebla; VER, Veracurz; YUC, Yucatán.