Table 1.
In vivo DTH response in pigs immunized with donor-derived class Ic or IIc peptides
| (A) mm of induration in animals immunized with class Ic peptides | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| animal | PC14-1 | PC14-2 | PC14-3 | MTB | RT1Du | ||||
| 16617 | 9 | 5 | 17 | 12 | 0 | ||||
| 16788 | 3 | 6 | 19 | 18 | 0 | ||||
| 16955 | 0 | 0 | 17 | 14 | 0 | ||||
| (B) mm of induration in animals immunized with class IIc peptides | |||||||||
|
| |||||||||
| animal | DR1 | DR2 | DR3 | DQ2 | DQ3 | DQ4 | DQ5 | MTB | RT1Du |
|
| |||||||||
| 16284 | 14 | 9 | 13 | 11 | 13 | 0 | 11 | 18 | 0 |
| 16486 | 12 | 7 | 10 | 5 | 8 | 0 | 5 | 15 | 0 |
| 16638 | 16 | 0 | 12 | 11 | 13 | 0 | 13 | 27 | 0 |
positive response: >10 mm
MTB : Mycobacterium tuberculosis H37 RA (positive control)
RT1Du: xenogeneic rat class II peptide (negative control)