TABLE 3.
Genes and gene products for selected H. influenzae resistance mechanismsa
| Gene | Gene product and description |
|---|---|
| blaTEM | TEM type β-lactamase; can be specified, as in blaTEM-1, to signify the gene associated with a specific TEM β-lactamase, such as TEM-1 |
| blaROB-1 | ROB-1 β-lactamase (although variants of this gene and enzyme have not been described, it is usual to use the suffix-1 with the gene and enzyme) |
| ftsI | PBP3 (see the text for discussion on PBP3A and PBPB) |
| dacA | PBP5 |
| dacB | PBP4 |
| acrA/acrB | AcrAB efflux pump |
| acrR | AcrR (repressor for AcrAB efflux pump) |
| tet(B) | Tet(B) tetracycline efflux protein |
| tet(M), tet(K) | Tet(M) and Tet(K) ribosomal protection proteins (reported only from non-H. influenzae Haemophilus spp.) |
| cat | Chloramphenicol acetyltransferase |