TABLE 1.

Main underlying diseases and comorbid conditions of patients with protothecosis

Underlying factor	No. of patients	References
Local or systemic steroid use	24	12, 27, 32, 45, 50, 52, 56, 66, 80, 84, 88, 92, 100, 109, 146, 151, 152, 162
Hematologic malignancy or cancer	16	15, 39, 53, 65, 74, 78, 85, 100, 144, 149, 150, 163
Diabetes mellitus	13	48, 56, 79, 88, 100, 149, 164, 165
AIDS	7	15, 62, 77, 107, 115, 116, 166
Organ transplantation	6	35, 56, 144, 146, 164, 165
Surgery	6	54, 56, 94, 100, 139, 149
Alcoholism	4	64, 100, 109
Peritoneal dialysis	3	48, 102, 130