. 2007 Apr;20(2):230–242. doi: 10.1128/CMR.00032-06

TABLE 2.

Unusual presentations of human protothecosis

Patient no.	Site(s) of infection	Prototheca sp. detected	Treatment^a	Outcome	Reference
1	Skin, blood	P. wickerhamii	AmB, transfer factor	Cured	34 ^b
2	Skin, fistula	P. wickerhamii	Tetracycline	Death from bacterial sepsis	35 ^b
3	Intestine	P. wickerhamii	None	Not given	24 ^b^,^c
4	Peritoneum	P. wickerhamii	AmB (intravenous and intraperitoneal)	Cured	102 ^b
5	Skin (extensive)	P. wickerhamii		Death from cancer	100 ^b
6	Gall bladder, liver	P. wickerhamii	AmB, ketoconazole	Cured	25 ^b
7	Peritoneum	P. wickerhamii	AmB (intravenous), doxycycline	Cured	130 ^b
8	Peritoneum	P. wickerhamii	AmB, 5-flucytosine	Cured	48 ^b
9	Respiratory tract	P. wickerhamii	AmB, excision	Cured	56 ^b
10	Blood, catheter	P. wickerhamii	AmB	Cured	53 ^b
11	Meninges	P. wickerhamii	AmB, 5-flucytosine	Death	62 ^b
12	Intestine, liver	P. wickerhamii	AmB, fluconazole	Not given	85 ^b
13	Intestine, lymph nodes	P. wickerhamii	AmB	Not given	85 ^b
14	Blood, urinary bladder	P. zopfii	Fluconazole	Death	76 ^b
15	Liver, meninges	P. wickerhamii	AmB, miconazole, fluconazole	Not eradicated in 6 yr	144 ^b
16	Blood, skin	P. wickerhamii	AmB, liposomal AmB	Cured	92 ^b
17	Endocardium	Prototheca spp.	AmB, excision	Cured	13 ^b
18	Skin, internal organs	P. wickerhamii	Fluconazole	Death	84 ^b
19	Ileum, duodenum	Prototheca spp.	AmB, itraconazole, gamma interferon	Cured	125 ^b
20	Skin, internal organs	Prototheca spp.	AmB	Death	163 ^b
21	Respiratory tract	Prototheca spp.	Fluconazole	Death	150
22	Blood, catheter	Prototheca spp.	Liposomal AmB	Cured	150
23	Skin, internal organs	P. zopfii	AmB, voriconazole	Death	78
24	Skin, blood	Prototheca spp.	AmB	Death	65
25	Skin, arthritis	P. wickerhamii	Itraconazole, AmB	Death	107

AmB, amphotericin B.

Reviewed in reference 12.

Possible case of protothecosis.