TABLE 1.

Analysis of serologic responses to VacA m1- and m2-specific antigens in 174 patients, according to H. pylori status

Serum sample group and antigen	OD for samples from patients who were:
	H. pylori negative			H. pylori positive
				m1 colonized			m2 colonized
	Range	Mean	Median	Range	Mean	Median	Range	Mean	Median
Unmodifieda
P44M1	0.028-5.108	0.524c	0.398	0.140-8.507	2.409c,d	1.688	0.094-4.896	0.598d	0.449
P48M2	0.069-5.599	0.478e,f	0.346	0.188-3.249	0.839e,g	0.665	0.028-5.432	0.729f,g	0.513
P55M2	0.023-9.293	0.759h	0.568	0.222-5.832	1.233i	0.902	0.072-8.546	1.642h,i	0.855
Selected samplesb
P48M2-mod	0.009-0.878	0.372j,k	0.334	0.188-1.302	0.551j,l	0.474	0.028-5.432	0.652k,l	0.493
P55M2-mod	0.023-1.382	0.574m	0.546	0.222-2.754	0.800n	0.684	0.072-8.546	1.065m,n	0.849

^aIncludes all serum samples from 77 H. pylori-negative patients and 32 m1-colonized and 65 m2-colonized, H. pylori-positive patients.

^bExcludes samples with a positive serologic response to P44M1 antigen; samples were from 72 H. pylori-negative patients and 10 m1-colonized and 59 m2-colonized, H. pylori-positive patients.

^cP = 2.0 × 10⁻¹⁰.

^dP = 8.0 × 10⁻⁹.

^eP = 0.012.

^fP = 0.047.

^gP = 0.503.

^hP = 0.002.

ⁱP = 0.791.

^jP = 0.046.

^kP = 0.013.

^lP = 0.669.

^mP = 0.006.

ⁿP = 0.486.