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Identification of neutralizing epitopes of DA6-7 and DA11-13 by phage display. (A) A phage-displayed random peptide library was screened by DA6-7. After three rounds of biopanning, 15 of 30 selected phage clones showed significant reactivity to antibody DA6-7 but not to control NMS. (B) A phage-displayed random peptide library was screened by DA11-13. After three rounds of biopanning, 32 of 36 selected phage clones showed significant reactivity to antibody DA11-13 but not to NMS.
