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. 2007 Feb 28;14(4):375–381. doi: 10.1128/CVI.00387-06

FIG. 3.

FIG. 3.

Rats (n = 10 per group) were immunized with either a high dose (100 μl of undiluted vaccine) or a low dose (100 μl of vaccine diluted 1:10) of trivalent split-virion influenza vaccine (Fluzone 2003-2004 formulation) and analyzed for serum antibody response 21 days later. Bars represent group GMT, and open symbols represent the responses from individual animals. (A) ELISA response against the H1N1 (A/NC/20/99) strain. (B) HAI response against the H1N1 (A/NC/20/99) strain. (C) ELISA response against the H3N2 (A/Pan/2007/99) strain. (D) HAI response against the H3N2 (A/Pan/2007/99) strain. (E) ELISA response against the B (B/HK/1434/02) strain. Due to insufficient quantities of sera from some animals, for analysis of ELISA titers against the B strain, only seven individuals from the i.d. “low-dose” group and nine animals from the i.m. “low-dose” group were analyzed. (F) HAI response against the B (B/HK/1434/02) strain.