FIG. 4.

Correlation between the percent live cells, as measured by the L/D FACS assay, and the anti-V Ab titers of sera from vaccinated CM. The increase in anti-V titer was compared to the viability of cells as measured by the FACS L/D assay in tests of sera collected over time during the vaccination period. The serum samples were collected during experiment 1 from the NHP vaccinated three times with F1-V vaccine. Analysis of the results with all of the combined sera collected prechallenge revealed that the titers were significantly correlated with the percent live cells (P < 0.0001). However, the Ab titers were not significantly associated with survival outcome (P > 0.05).