TABLE 2.
Cross-reactivity in clinical specimens and experimental infection
| Specimen source | Assayf | No. of specimens positive for antigen/no. tested
|
|
|---|---|---|---|
| Aspergillus | Cryptococcus | ||
| Infected patients | Af GalM EIA | 20/20a | 0/25b |
| Cn CPS LA | 0/20a | 24/25b | |
| Mice experimentally infected | Af GalM EIA | 5/5a | 0/8c |
| with C. neoformans | Cn CPS LA | 0/5a | 8/8c |
| Rabbits experimentally | Af GalM EIA | 7/7d | 0/8e |
| infected with A. fumigatus | Cn CPS LA | 0/7d | 8/8e |
Serum.
Serum or CSF.
Spleen tissue.
BAL fluid.
Lung tissue.
Af, A. fumigatus; Cn, C. neoformans.