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CD-specific serum antibodies after intranasal immunization with nCD or rCD using AdDP as the mucosal adjuvant. The data are presented as the reciprocal log2 mean endpoint titers, and the error bars indicate standard errors of the means. Differences were statistically significant at P values of <0.0001 (one asterisk) and <0.0005 (two asterisks) for comparisons with the control groups.
