FIG. 5.

M. catarrhalis recovery from lung homogenates obtained from mice intranasally vaccinated with either nCD or rCD coadministered with AdDP. Immunized mice were challenged by the intratracheal route with 5 × 10⁸ CFU of M. catarrhalis. Bacterial clearance was assessed after 4 h by plating serial dilutions of the lung homogenates onto BHI agar plates. The data are presented as the mean numbers of CFU/lung; the error bars indicate standard errors of the means. An asterisk indicates that the difference was statistically significant at a P value of <0.03 for a comparison with the AdDP control group.