FIG. 3.

S. maltophilia lung infection. (A) Percentages of C57BL/6 mice (Wild type) and TNFR1 null mice that developed pneumonia or bacteremia or died. Two asterisks indicate that the P value is <0.01 for a comparison with wild-type mice inoculated with N3. (B) Percentages of PMNs in the total leukocytes in the lungs of wild-type and TNFR1 null mice. Each symbol represents an individual mouse, and the lines indicate the medians for the groups. One asterisk indicates that the P value is <0.05 and two asterisks indicate that the P value is <0.01 for a comparison with control mice inoculated with phosphate-buffered saline (C). (C) Lung TNF-α mRNA expression in TNFR1 null mice as determined by real-time PCR and standardized to actin. Each symbol represents an individual mouse, and the lines indicate the medians for the groups. The asterisk indicates that the P value is <0.05 for a comparison with control mice inoculated with phosphate-buffered saline.