The levels of IFN-γ and IL-12 secreted by MLNC isolated at day 42 p.i. were determined in WT, p55−/−, and p75−/− animals by ELISA. Each value represents the mean of four animals ± the SEM. *, ANOVA and the Tukey test showed a statistically significant increase in infected versus naive animals; Ψ, statistically significant difference between WT and gene-deficient mice (P < 0.05). Bars: □, naive animals; ▪, infected animals. ND, not detected. All cytokine levels shown are over the limit of detection.