TABLE 4.

Susceptibility of patients with different PIDs to Pneumocystis carinii infections

PID with indicated level of susceptibility:
High	Intermediate	Low
All SCID types (11, 12, 105) MHC-II deficiency (45, 57) ZAP 70 deficiency (37, 45) Idiopathic CD4 lymphocytopenia (45, 103) X-linked hyper-IgM syndrome (CD40L deficiency) (65, 66, 114) AR-hyper-IgM type 3 (CD40 deficiency) (68)	XL agammaglobulinemia (19, 64, 88) CVID (22) Wiskott-Aldrich syndrome (106) XL-EDA-ID (NEMO defects) (61, 83) Hyper-IgE syndrome (50, 51)	Predominantly antibody deficiencies (except some cases of XLA and CVID) (21, 46, 84, 91, 101) MHC-I deficiencies (TAP-1and TAP-2 defects) (32, 47, 69, 73, 119) Complement deficiencies (43, 107) IL-12/IL-23-IFN-γ axis deficiencies (33, 36, 42, 85) Neutropenias (9, 25) Chronic granulomatous disease (1, 15, 113) Chédiak-Higashi syndrome (55) IRAK-4 deficiency (23, 38, 61, 70, 86, 110) Ataxia-telangiectasia syndrome (79) Asplenia (48, 99)