TABLE 5.

Reported clinical associations between PIDs and different fungal infections

PID associated with indicated fungus:
Candida	Aspergillus fumigatus	Cryptococcus neoformans	Histoplasma capsulatum
APECED (2, 6) Other forms of chronic mucocutaneous candidiasis (45) Hyper-IgE syndrome (10, 50, 65) SCID (11, 12, 105) MHC-II deficiency (57) Idiopathic CD4 lymphocytopenia (103) XL-EDA-ID (defects of NEMO) (60, 83) Myeloperoxidase deficiency in diabetic patients (97) Wiskott-Aldrich syndrome (106)	Chronic granulomatous disease (3, 15, 113) Hyper-IgE syndrome (3, 50) SCIDa (117) Leukocyte adhesion deficiencies (LADs) (97) Idiopathic CD4 lymphocytopenia (45)	Idiopathic CD4 lymphocytopenia (103) Hyper-IgE syndrome (10, 50)	Idiopathic CD4 lymphocytopenia (103) XL hyper-IgM syndrome (CD40L deficiency) (114) Hyper-IgE syndrome (50) Autosomal dominant form of IFN-γ receptor 1 deficiencya (118)

^aOnly one case has been reported.