FIG. 4.

Suppression of CFU-E growth by IFN-γ is IL-15 dependent. Bone marrow cells from wild-type (WT) or IL-15-deficient (KO) mice were cultured in triplicate. The indicated cytokines and antibodies were added to the medium at the initiation of culture. The asterisks depict significant differences for the comparisons indicated, as determined by Student's t test (two asterisks, P < 0.005; one asterisk, P < 0.03; n.s., not significant). The data are averages of data pooled from two independent experiments. The absolute number of CFU-E in control cultures ranged from 232 to 860. IgG, immunoglobulin G.