TABLE 3.
Results of conventional methods and PCR in 200 patients with brucellosis during treatment surveillance
| Methoda | No. (%)b
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Antibiotic treatmentc
|
Follow-up after the end of treatmentd
|
|||||||
| Pre | Post | Mo 1 | Mo 2 | Mo 3 | Mo 6 | Mo 9 | Mo 12 | |
| Blood culture | 148 (74) | ND | ND | ND | ND | ND | ND | ND |
| SAT ≥1:160 | 181 (90.5) | 158 (79) | 132 (66) | 119 (59.5) | 101 (50.5) | 52 (26) | 53 (26.5) | 46 (23) |
| CT ≥1:320 | 131 (65.5) | 115 (57.5) | 112 (56.0) | 109 (54.5) | 108 (54.0) | 92 (46) | 86 (43) | 81 (40.5) |
| CF ≥1:16 | 155 (77.5) | 131 (65.5) | 129 (64.5) | 126 (63.0) | 125 (62.5) | 120 (60) | 114 (57) | 92 (46) |
| PCR A, bc | 200 (100) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) |
| PCR A, wb | 198 (99) | 17 (8.5) | 16 (8) | 16 (8) | 17 (8.5) | 15 (7.5) | 16 (8) | 17 (8.5) |
| PCR A, se | 194 (97) | 9 (4.5) | 8 (4) | 9 (4.5) | 9 (4.5) | 10 (5) | 8 (4) | 9 (4.5) |
| PCR B, bc | 200 (100) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) |
| PCR B, wb | 196 (98) | 17 (8.5) | 15 (7.5) | 15 (7.5) | 16 (8) | 15 (7.5) | 17 (8.5) | 16 (8) |
| PCR B, se | 191 (95.5) | 9 (4.5) | 7 (3.5) | 7 (3.5) | 8 (4) | 9 (4.5) | 9 (4.5) | 7 (3.5) |
| PCR C, bc | 200 (100) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) |
| PCR C, wb | 198 (99) | 17 (8.5) | 17 (8.5) | 16 (8) | 17 (8.5) | 16 (8) | 17 (8.5) | 16 (8) |
| PCR C, se | 194 (97) | 9 (4.5) | 8 (4) | 10 (5) | 9 (4.5) | 7 (3.5) | 8 (4) | 9 (4.5) |
| PCR D, bc | 200 (100) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) | 17 (8.5) |
| PCR D, wb | 197 (98.5) | 17 (8.5) | 16 (8) | 17 (8.5) | 16 (8) | 16 (8) | 17 (8.5) | 15 (7.5) |
| PCR D, se | 193 (96.5) | 9 (4.5) | 9 (4.5) | 8 (4) | 9 (4.5) | 6 (3) | 8 (4) | 7 (3.5) |
a
For SAT, CT, and CF the titer result is indicated. bc, buffy coat; wb, whole blood; se, serum.
b
No., number of patients with positive result; %, proportion of positive results. ND, not done.
c
Pre, at admittance (before antibiotic treatment); Post, end of antibiotic treatment.
d
The time point in months after the end of therapy is indicated.