TABLE 3.
Association of ethnicity with CMV antigenemia among allo-SCT patients
| Underlying disease | No. of patients positive for CMV antigenemia/no. tested (%)
|
P value for whites vs those of other ethnicities
|
|||||
|---|---|---|---|---|---|---|---|
| White | Black | Asian | Hispanic | Black | Asian | Hispanic | |
| Acute lymphoblastic leukemia | 34/88 (38.6) | 3/7 (42.9) | 13/14 (92.9)a | 16/41 (39.0) | NSb | <0.001 | NS |
| Chronic lymphocytic leukemia | 33/80 (41.3) | 1/1 (100) | 1/1 (100) | 1/3 (33.3) | |||
| Lymphoma | 88/261 (33.7) | 4/8 (50.0) | 7/11 (63.6) | 22/50 (44.0) | NS | 0.041 | NS |
| Multiple myeloma | 15/30 (50.0)c | 4/6 (66.7) | 0/0 (0) | 6/8 (75.0)d | NS | NS | |
| Myeloid and other hematologic diseases | 155/436 (35.6) | 14/33 (42.4) | 23/44 (52.3) | 42/108 (38.9) | NS | 0.029 | NS |
| Solid tumors and other nonhematologic diseases | 18/46 (39.1) | 1/1 (100) | 0/2 (0) | 3/10 (30.0) | NS | ||
| Total | 343/941 (36.5) | 27/56 (48.2) | 44/72 (61.1) | 90/220 (40.9) | 0.077 | <0.001 | NS |
For Asians with acute lymphoblastic leukemia (13/14) versus Asians with all other diseases combined (31/58), χ2 = 7.37 and P = 0.007; for Asians with acute lymphoblastic leukemia (13/14) versus whites with acute lymphoblastic leukemia (34/88), χ2 = 14.3 and P < 0.001; for Asians with acute lymphoblastic leukemia (13/14) versus Hispanics with acute lymphoblastic leukemia (16/41), χ2 = 12.1 and P < 0.001; for Asians with acute lymphoblastic leukemia (13/14) versus blacks with acute lymphoblastic leukemia (3/7), P = 0.025 (by Fisher exact test).
NS, not significant.
For whites with myeloma (15/30) versus those with all other diseases (328/911), relative risk = 1.39, χ2 = 2.46, and P was not significant.
For Hispanics with myeloma (6/8) versus those with all other diseases (84/212), relative = 1.89, χ2 = 3.99, and P = 0.046.