. 2007 Jan 17;45(4):1298–1304. doi: 10.1128/JCM.02115-06

TABLE 1.

Frequency of HHV-6 DNA in the CSF of immunocompetent children with primary infection

Patient no. (sex)^a	Age at onset of illness	Presence of HHV-6 DNA in acute-phase serum (variant)	CSF		Clinical details
Patient no. (sex)^a	Age at onset of illness	Presence of HHV-6 DNA in acute-phase serum (variant)	No. of days after onset of illness that sample was taken	Presence of HHV-6 DNA (variant, log₁₀ HHV-6 DNA copies/ml)	Clinical details
P1 (F)^b	4 mo	+ (B)	0^c	−	Fever, rash, possible encephalitis/meningitis
P2 (M)^b^,^d	9 mo	+ (B)	0	−	Fever, convulsions
P3 (F)^d	10 mo	−	1	+ (B, 1.6)	Fever, convulsions
P4 (F)^d	11 mo	+ (B)	0	−	Fever, rash, convulsions
P5 (M)^b^,^d	11 mo	+ (B)	3	−	Fever, rash, convulsions
			5	+ (B, 3.6)	Fever, rash, convulsions
P6 (M)^b^,^d	1 yr	+ (B)	1	+ (B, 2.6)	Fever, convulsions
P7 (F)^b^,^d	1 yr	+ (B)	1	−	Fever, rash, convulsions
P8 (M)^d	1 yr, 3 mo	−	1	+ (NT, NT)	Fever, rash, convulsions
P9 (M)^b^,^d	1 yr, 8 mo	+ (B)	1	+ (B, 1.6)	Fever, encephalopathy

Further details for patients have been reported elsewhere (41, 47). M, male; F, female.

Primary infection defined by low concentration HHV-6 DNA, i.e., <3.0 log₁₀ HHV-6 DNA copies/ml in an acute seronegative serum.

Day of onset of illness unknown so day of first sample defined as 0.

Primary infection defined by seroconversion to HHV-6 IgG between acute- and convalescent-phase sera.