TABLE 3.
Patient ID | pVL (copies/ml) | Time (mo) | % CD4+ CD3+ | CD4 count | cVL (copies/105 cells) | iVL (copies/105 cells) | Therapyb | Other drug therapyc | Therapy outcomed |
---|---|---|---|---|---|---|---|---|---|
1 | <400 | 25 | 12 | 465 | 414 | ND | TRIZ, EFV | ||
2 | <50 | >81 | 33 | 971 | 1,584 | 3 | |||
3 | <50 | >16 | 26 | 327 | 3,540 | 18 | COM, K | Y | |
4 | <400 | 80 | 24 | 410 | 3,485 | 4 | |||
5 | <400 | 57 | 29 | 641 | 2,011 | 12 | COM, NVP | ||
6 | <400 | 29 | 8 | 196 | 32 | 14 | ABC, 3TC, NVP | ||
<400 | 297 | ND | ND | ABC, 3TC, NVP | |||||
<40 | 12 | 354 | 287 | 21 | ABC, 3TC, NVP | ||||
7 | <400 | >16 | 35 | 651 | 47 | 36 | 3TC, STAV, NVP | ||
<40 | 767 | 87 | 66 | 3TC, EFV, ABC | |||||
<40 | 36 | ND | 3TC, EFV, ABC | ||||||
8 | <400 | 53 | 26 | 532 | 5,110 | 10 | COM, NVP | Y | |
<400 | 57 | 29 | 641 | 2,011 | 60 | COM, NVP | |||
9 | <400 | 77 | 27 | 327 | 11,608 | 3 | |||
<400 | 80 | 24 | 410 | 3,485 | 4 | ||||
10 | <50 | 18 | 16 | 325 | 2,535 | 38 | COM, K | F | |
11 | 35,500 | 14 | 473 | 18 | 8 | ||||
12 | <50 | >24 | 26 | 575 | 170 | INV | EFV, COM | ||
<40 | >30 | 29 | 612 | 99 | 16 | EFV, COM | |||
13 | <400 | 222 | INV | ||||||
14 | <50 | >69 | 18 | 173 | 164 | ND | |||
15 | 205,000 | 229 | INV | ||||||
16 | 800 | 30 | 457 | 382 | INV | COM, EFV | |||
17 | <400 | 68 | 10 | 243 | 9 | ND | 3TC, TDF, EFV | Y | |
18 | <50 | 21 | 527 | 47 | 76 | TRIZ, NVP | Y | ||
19 | <50 | >10 | 13 | 351 | 226 | 211 | TDF, 3TC, EFV | Y | F |
20 | <400 | 22 | 13 | 433 | 8,584 | INV | TRIZ, EFV | Y | |
21 | 87,000 | 13 | 103 | 129 | 36 | NVP, COM | Y | ||
22 | <400 | >24 | 38 | 26 | ND | COM, NVP | |||
<40 | >18 | 36 | 1,270 | 73 | 6 | COM, NVP | |||
23 | <400 | 19 | 37 | 1,059 | 27 | 43 | AZT, 3TC, NVP | F | |
24 | 10,000 | 14 | 321 | 1,714 | INV | 3TC, STAV | Y | ||
25 | 1,700 | 22 | 403 | 6 | ND | TRIZ | |||
210 | 36 | 35 | TRIZ, ATAZ | F | |||||
26 | <50 | >78 | 22 | 437 | ND | ND | |||
27 | 89,000 | 14 | 112 | ND | 3TC, K, TDF | Y | |||
47,000 | 13 | 151 | 43 | ND | 3TC, K, TDF | Y | |||
28 | <50 | 22 | 31 | 357 | 152 | ND | COM, EFV | ||
29 | <400 | >78 | 8 | 278 | 156 | INV | |||
30 | 1,900 | 12 | 107 | 10 | INV | COM, EFV | Y | ||
110 | >11 | 14 | 287 | 9,458 | INV | EFV, TRIZ, RTV | |||
>12 | 13 | 310 | ND | ND | COM, EFV | ||||
31 | 4,000 | 16 | 347 | 123 | INV | ||||
32 | <400 | 42 | 18 | 234 | 30,481 | 37 | |||
<400 | 45 | 21 | 305 | 1,176 | 7 | ||||
33 | 800 | 26 | 531 | 247 | 102 | 3TC, K, TDF | |||
34 | <50 | >81 | 33 | 971 | 1,584 | 9 | |||
35 | <400 | 45 | 52 | 1,088 | 19 | ND | |||
36 | 2,300 | 30 | 540 | 10 | ND | TDF, 3TC, K | |||
37 | <400 | 35 | 19 | 307 | 10 | INV | AZT, 3TC, NVP | Y | |
38 | 27,000 | 41 | 628 | 88 | 84 |
ND, not detected or below the limit of the assay; INV, invalid (result from Alu-minus control PCR greater or equal to Alu PCR).
TRIZ, Trizivir; EFV, efavirenz; COM, Combivir; K, Kaletra; NVP, nevirapine; ABC, abacivir; 3TC, lamivudine; STAV, stavudine; TDF, tenofovir; RTV, ritonavir; ATZ, atazanavir.
A Y indicates that other drug therapy included antidepressant, antifungal, and antibacterial drugs.
An F indicates that at 12 months postmeasurement, treatment had failed.