TABLE 2.
Clinical signs and symptoms associated with the presence of C. trachomatis infection by multivariate analysis
Variable or clinical sign or symptom | Female patients
|
Male patients
|
||||||
---|---|---|---|---|---|---|---|---|
Crude ORa | P for crude OR | Adjusted ORb | P for adjusted OR | Crude ORc | P for crude OR | Adjusted OR | P for adjusted OR | |
Age group | ||||||||
<30 yr vs ≥30 yr | 4.20 (1.76-10.1) | 0.0005 | 4.13 (1.88-9.07) | 0.0002 | ||||
<25 yr vs ≥25 yr | 2.71 (1.47-5.00) | 0.001 | 1.23 (0.66-2.32) | 0.514 | ||||
Patient-reported symptoms | ||||||||
Symptomatic vs asymptomatic | 1.91 (1.04-3.50) | 0.033 | 5.67 (2.81-11.5) | <0.0001 | ||||
Dysuria | 4.28 (1.87-9.82) | 0.0002 | 3.92 (1.42-10.9) | 0.0086 | 8.27 (4.35-15.7) | <0.0001 | 4.42 (1.51-12.1) | 0.0011 |
Urethral itching | NA | 6.15 (1.80-21.0) | 0.0011 | 13.7 (2.96-63.0) | 0.0008 | |||
Vaginal/urethral irritation | 0.14 (0.02-1.04) | 0.026 | 2.17 (0.97-4.89) | 0.055 | ||||
Pelvic or abdominal pain | 2.63 (1.32-5.24) | 0.004 | 3.39 (1.40-8.18) | 0.0066 | NA | |||
Reported abnormal discharge | ||||||||
Patient reported vs none | 3.38 (1.47-7.80) | 0.004 | 5.50 (2.33-13.0) | <0.0001 | ||||
Doctor reported vs none | 3.15 (1.33-7.45) | 0.009 | 3.53 (1.29-9.61) | 0.014 | 14.3 (3.82-53.5) | <0.0001 | 7.60 (1.30-44.3) | 0.024 |
Doctor or patient reported vs none | 7.37 (3.40-16.0) | <0.0001 | 4.78 (1.99-11.5) | 0.0005 | 10.2 (4.58-22.8) | <0.0001 | 4.27 (1.51-12.1) | 0.0063 |
Clinical signs | ||||||||
PMNLs/HPF | 1.04 (1.02-1.07) | 0.0008 | 8.27 (4.35-15.7) | <0.0001 | 4.42 (1.81-10.8) | 0.0011 | ||
NSU or NSC vs neitherd | 3.71 (2.00-6.87) | <0.0001 | 3.98 (1.87-8.47) | 0.0003 | 15.2 (7.07-32.6) | <0.0001 | 7.56 (2.98-19.2) | <0.0001 |
Cervical contact bleeding | 13.2 (4.24-41.0) | <0.0001 | 11.7 (2.28-60.5) | 0.0032 | NA | |||
Moist urethral meatus | NA | 7.66 (3.17-18.5) | <0.0001 | 5.95 (1.86-19.0) | 0.0027 | |||
Coinfections | ||||||||
Molluscum contagiosum | 21.3 (3.8-119.5) | <0.0001 | 53.0 (6.04-466) | 0.0003 | ||||
Genital warts | 2.15 (0.95-4.90) | 0.062 | 6.11 (2.30-16.2) | 0.0003 | ||||
One or more infections | 1.86 (1.01-3.41) | 0.043 | ||||||
Traced STI contacts | ||||||||
C. trachomatis contact | 13.3 (4.86-36.2) | <0.0001 | 9.08 (2.50-32.9) | 0.0008 | 4.05 (1.43-11.5) | 0.0048 | 13.5 (3.32-54.8) | 0.0003 |
NSU contact | 2.70 (1.11-6.54) | 0.023 | NA |
OR, odds ratio. Numbers in parentheses after odds ratios represent the 95% CI. NA, not applicable to gender.
Only those variables that remained significant after adjustment for other variables in the model are included.
Lack of data for the crude odds ratio is due to the low prevalence of the variable.
NSU, nonspecific urethritis; NSC, nonspecific cervicitis.