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. 2007 Mar 21;45(5):1395–1402. doi: 10.1128/JCM.00100-07

TABLE 2.

Clinical signs and symptoms associated with the presence of C. trachomatis infection by multivariate analysis

Variable or clinical sign or symptom Female patients
Male patients
Crude ORa P for crude OR Adjusted ORb P for adjusted OR Crude ORc P for crude OR Adjusted OR P for adjusted OR
Age group
    <30 yr vs ≥30 yr 4.20 (1.76-10.1) 0.0005 4.13 (1.88-9.07) 0.0002
    <25 yr vs ≥25 yr 2.71 (1.47-5.00) 0.001 1.23 (0.66-2.32) 0.514
Patient-reported symptoms
    Symptomatic vs asymptomatic 1.91 (1.04-3.50) 0.033 5.67 (2.81-11.5) <0.0001
    Dysuria 4.28 (1.87-9.82) 0.0002 3.92 (1.42-10.9) 0.0086 8.27 (4.35-15.7) <0.0001 4.42 (1.51-12.1) 0.0011
    Urethral itching NA 6.15 (1.80-21.0) 0.0011 13.7 (2.96-63.0) 0.0008
    Vaginal/urethral irritation 0.14 (0.02-1.04) 0.026 2.17 (0.97-4.89) 0.055
    Pelvic or abdominal pain 2.63 (1.32-5.24) 0.004 3.39 (1.40-8.18) 0.0066 NA
Reported abnormal discharge
    Patient reported vs none 3.38 (1.47-7.80) 0.004 5.50 (2.33-13.0) <0.0001
    Doctor reported vs none 3.15 (1.33-7.45) 0.009 3.53 (1.29-9.61) 0.014 14.3 (3.82-53.5) <0.0001 7.60 (1.30-44.3) 0.024
    Doctor or patient reported vs none 7.37 (3.40-16.0) <0.0001 4.78 (1.99-11.5) 0.0005 10.2 (4.58-22.8) <0.0001 4.27 (1.51-12.1) 0.0063
Clinical signs
    PMNLs/HPF 1.04 (1.02-1.07) 0.0008 8.27 (4.35-15.7) <0.0001 4.42 (1.81-10.8) 0.0011
    NSU or NSC vs neitherd 3.71 (2.00-6.87) <0.0001 3.98 (1.87-8.47) 0.0003 15.2 (7.07-32.6) <0.0001 7.56 (2.98-19.2) <0.0001
    Cervical contact bleeding 13.2 (4.24-41.0) <0.0001 11.7 (2.28-60.5) 0.0032 NA
    Moist urethral meatus NA 7.66 (3.17-18.5) <0.0001 5.95 (1.86-19.0) 0.0027
Coinfections
    Molluscum contagiosum 21.3 (3.8-119.5) <0.0001 53.0 (6.04-466) 0.0003
    Genital warts 2.15 (0.95-4.90) 0.062 6.11 (2.30-16.2) 0.0003
    One or more infections 1.86 (1.01-3.41) 0.043
Traced STI contacts
    C. trachomatis contact 13.3 (4.86-36.2) <0.0001 9.08 (2.50-32.9) 0.0008 4.05 (1.43-11.5) 0.0048 13.5 (3.32-54.8) 0.0003
    NSU contact 2.70 (1.11-6.54) 0.023 NA
a

OR, odds ratio. Numbers in parentheses after odds ratios represent the 95% CI. NA, not applicable to gender.

b

Only those variables that remained significant after adjustment for other variables in the model are included.

c

Lack of data for the crude odds ratio is due to the low prevalence of the variable.

d

NSU, nonspecific urethritis; NSC, nonspecific cervicitis.