TABLE 3.
Independent risk factors predictive for HCC development in HBV patients as determined by multivariate analysis
| Factor | Odds ratio (95% CI) | P value |
|---|---|---|
| Age | ||
| <50 yr | 1 | 0.001 |
| ≥50 yr | 14.25 (3.16-64.16) | |
| Sex | ||
| Female | 1 | 0.81 |
| Male | 0.83 (0.18-3.91) | |
| HBeAg status | ||
| Negative | 1 | 0.07 |
| Positive | 0.32 (0.10-1.10) | |
| Genotype | ||
| B | 1 | 0.591 |
| C | 1.50 (0.34-6.56) | |
| C1653T mutation | ||
| Absence | 1 | 0.007 |
| Presence | 20.62 (2.33-182.36) | |
| T1753V mutation | ||
| Absence | 1 | 0.013 |
| Presence | 5.63 (1.45-21.84) | |
| A1762T G1764A mutation | ||
| Absence | 1 | 0.008 |
| Presence | 5.50 (1.58-19.18) | |
| 1896A mutation | ||
| Absence | 1 | 0.17 |
| Presence | 2.52 (0.67-9.41) | |
| 1898A mutation | ||
| Absence | 1 | 0.551 |
| Presence | 2.05 (0.19-21.81) | |
| 1899A mutation | ||
| Absence | 1 | 0.966 |
| Presence | 1.03 (0.22-4.84) |