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. 2006 Dec 6;81(5):2340–2348. doi: 10.1128/JVI.01310-06

FIG. 6.

FIG. 6.

PIKE-A inhibits activation of apoptosis in type II (786-0) cells infected with vMyxT5KO and type III (MDA-MB435) cells infected with vMyxlac and vMyxT5KO. Human renal cancer 786-0 (type II) cells (A and B) and breast cancer MDA-MB435 (type III) cells (C and D) were transfected with PIKE-A plasmid (B and D) or mock transfected (A and C) and 8 h later were infected with either vMyxlac (A to D, lanes 1 to 6) or vMyxT5KO (A to D, lanes 7 to 12) at an MOI of 5. Cells were harvested at the indicated times postinfection, and the cell lysates (50 μg per lane) were probed by immunoblotting for procaspase 3 degradation.