FIG. 3.
Identification of the optimal epitope. IFN-γ responses were measured using truncated or mutated peptides. At day 5 (filled squares) or day 12 (open squares) after the second infection, animals were sacrificed and splenocytes were stimulated with the peptides indicated in Table 2. Data represent the results of an average of eight replicates. Group A, negative control medium or peptide; group B, truncated or mutated peptides for the subdominant epitope; group C, immunodominant epitope M282-90.