FIG. 6.

Proliferation of off-therapy PBMC to HIV Gag peptides is rescued by a soluble factor produced by on-therapy cells. A. Proliferation of combinations of off-therapy and on-therapy PBMC separated by a 0.4-μm transwell insert to HIV Gag peptides. The upper chamber contained 250,000 cells and the lower chamber 750,000 cells. CD4⁺ T cells displayed in plots are from the time point indicated by the arrows. Proliferation was similar in upper and lower chambers when PBMC from the same time point were utilized. B. Summary of data on proliferative responses to HIV Gag peptides from eight patients undergoing treatment interruption.