TABLE 1.
Virus titers in various organs of rhesus macaques infected with wild-type Ebola virus (ZEBOV) or with an Ebola virus lacking the consensus furin recognition motif in GP (ZEBOVΔCleav)
| Virus strain (animal no.) | Virus titer (log10 of PFU/gram tissue on day 7 postinfection)a
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liver | Spleen | Kidney | Lungs | Pancreas | Brain | Heart | Bone marrow | Testis | Adrenal glands | Axillary lymph nodes | Inguinal lymph nodes | Mesenteric lymph nodes | Mandibular lymph nodes | |
| ZEBOV (1) | 6.93 | 7.41 | 5.51 | 5.50 | 2.40 | 3.98 | 4.93 | 6.15 | 5.81 | 6.01 | 6.20 | 7.12 | 6.68 | 6.01 |
| ZEBOV (2) | 6.95 | 7.40 | 6.70 | 6.10 | 6.51 | 5.01 | 5.31 | 6.08 | 6.75 | 7.07 | 6.79 | 6.47 | 7.86 | 6.90 |
| ZEBOV ΔCleav (1) | 5.54 | 2.87 | 6.10 | 6.74 | 0 | 6.22 | 5.97 | 5.90 | 6.22 | 5.65 | 6.37 | 6.26 | 5.89 | 6.30 |
| ZEBOV ΔCleav (2) | 7.80 | 7.70 | 5.87 | 4.23 | 5.65 | 5.31 | 5.83 | 6.90 | 6.60 | 7.33 | 6.76 | 6.59 | 7.44 | 7.05 |
a
Animals were inoculated in the caudal thigh with 103 PFU of virus.