FIG. 2.

Inhibition of pseudotype infection by HNG-105. Recombinant luciferase-containing viruses pseudotyped with the envelope proteins from different HIV-1 isolates were used in single-round infection assays in the presence of increasing concentrations of HNG-105. HOS cells stably expressing CD4 and CCR5 were used as target cells for R5 viruses, whereas U87 cells stably expressing CD4 and CXCR4 were used for X4 viruses. For the sake of clarity, the data have been distributed into two panels, A and B. The subtype of each HIV-1 strain is given in parentheses after the variant name.