FIG. 3.

Passage history of CWD inocula in rodent species. Primary inocula used were brain homogenates of each species (e, elk; md, mule deer; and wd, white-tailed deer) from either individual CWD-positive animals (A) or brain pools from CWD-affected animals of each species (B). The individual brains were passaged serially three times in the rodent species indicated, whereas the pooled brain samples were passaged only one time in the various species shown. Since there were no positive RML mice from the primary passage of the individual positive cervid brains, no additional passes were done. ha, hamster; Sib, Siberian; Djun, Djungarian; Arm, Armenian; Chin, Chinese; mo, mouse.