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. 2007 Jan 31;81(8):3992–4001. doi: 10.1128/JVI.02395-06

FIG. 1.

FIG. 1.

ETV structure and hydrogen bonding network with HBV RT. (A) Chemical structures of deoxyguanosine, the deoxyguanosine analog ETV, the cytosine analog LVD, the adenosine monophosphonate analog ADV, and the thymidine analog LdT. (B) Hydrogen bonding network between ETV-TP and HBV RT. Note that the hydrogen bonding network between the triphosphate moiety and HBV RT is conserved for all NRTI-TPs and natural nucleotides. Only ETV and the natural nucleotides show the hydrogen bond between F88 and the 3′-hydroxyl group.