Table 2.

Genes with Alternatively Polyadenylated Transcripts in Contig NT_011515 of Chromosome 21^a

Reference transcript	UniGene cluster	Description	No. of tags	Extent
D80001	Hs.152629	KIAA0179 protein	6	11 kb
NM_003681	Hs.38041	Pyridoxal (pyridoxine, vitamin B6) kinase	6	7 kb
NM_021941	Hs.4746	Hypothetical protein FLJ21324
NM_000100	Hs.695	Cystatin B (stefin B)	2	1.4 kb
AI885390	Hs.49031	ESTs
NM_003683	Hs.110757	NNP-1/Nop52, novel nuclear protein 1	2	1.2 kb
NM_020132	Hs.324020	1-acylglycerol-3-phosphate O-acyltransferase 3	10	5.5 kb
AK026135	Hs.173138	FLJ22482 fis, clone HRC10859
NM_031487	Hs.284123	hypothetical protein MGC4604
NM_003274	Hs.94479	Transmembrane protein 1	5	2 kb
AF289028	Hs.14155	KIAA0653 protein, B7-like protein	3	5 kb
NM_013369	Hs.157237	DNA (cytosine-5-)-methyltransferase 3-like	3	0.9 kb
AI652007	(cluster retired)
NM_000383	Hs.129829	Autoimmune regulator	2	0.6 kb
NM_002626	Hs.155455	Phosphofructokinase, liverb	4	14 kb
N22796	Hs.12561	ESTs
AA813142	Hs.323133	ESTs
NM_004928	Hs.153452	Chromosome 21 open reading frame 2	2	1.1 kb
AJ003549	Hs.278715	Chromosome 21 open reading frame 31	2	2.2 kb
AJ003544	Hs.125774	ESTs
T83849	Hs.194595	ESTs
NM_003343	Hs.192853	Ubiquitin-conjugating enzyme E2G 2	2	2.3 kb
NM_006936	Hs.85119	SMT3 (suppressor of mlf two 3, yeast) homolog	5	1.2 kb
NM_004339	Hs.111126	Pituitary tumour-transforming 1 interacting protein	5	1.5 kb
NM_001112	Hs.85302	Adenosine deaminase, RNA-specific, B1	2	4.2 kb
NM_015227	Hs.22982	KIAA0958 protein	2	0.9 kb
AL390181	Hs.170144	CDNA DKFZp547J125	6	0.9 kb
NM_016214	Hs.78409	Collagen, type XVIII, alpha 1c	3	2.6 kb
BF110399	Hs.84190	Solute carrier family 19 (folate transporter), member 1
NM_003056	Hs.84190	Solute carrier family 19 (folate transporter), member 1	4	2.6 kb
NM_001848	Hs.108885	Collagen, type VI, alpha 1	2	1 kb
X15882	Hs.159263	Collagen, type VI, alpha 2	3	3 kb
NM_002340	Hs.93199	2,3-oxidosqualene-lanosterol cyclase	2	1 kb
NM_003906	Hs.188481	Minichromosome maintenance deficient 3-associated protein	2	2.2 kb
AA527431	Hs.178588	ESTs
NM_006272	Hs.83384	S100 calcium-binding protein, beta (neural)	2	0.3 kb
NM_001535	Hs.235887	HMT1 (hnRNP methyltransferase)-like 1d	>6	∼15 kb

^aThe distribution of transcript sequences and 3′ tags on the genome was visualized using ACEDB (see Fig. 1). The reference transcript was chosen from the NCBl curated RefSeq, EMBL human, or EST databases, in this order of preference. Transcripts matching multiple UniGene clusters are shown on multiple lines. The “Extent” column shows the distance separating the first from the last documented 3′ tag. 

^bThe 3′ UTR overlaps the entire extent of the C21orf2 gene on the other strand. 

^cThe 3′ UTR overlaps that of the folate transporter gene on the other strand. See the main text and Figure 1b for details. 

^dThis gene shows a very complex pattern of alternative splicing and polyadenylation that will require additional experimental data to sort out. 

EST, expressed sequence tag; UTR, untranslated region.