Fig. 7.
HCV neutralization in cell culture. (A) HCV neutralization by Ig eluates. The x axis indicates Ig eluates that were used in this assay at 1:40 dilution. HCIGIV at 1:100 dilution was used as the positive control, and an IGIV (5%) at 1:100 dilution was used as the negative control. The y axis indicates infectivity (percentage of negative control). The asterisk indicates statistical significance (P < 0.05). (B) Blocking neutralizing activity of DE by nonneutralizing Ig in AE. The x axis indicates Ig AE or DE alone at 1:40 dilution or a mixture of AE and DE (AE + DE) at 1:1 or 2:1 ratio. An IGIV (5%) at 1:100 dilution was used as the negative control. The y axis indicates infectivity (percentage of negative control). The asterisk indicates statistical significance (P < 0.05).
