COILS prediction of SMC2 and SMC4 orthologs. The
COILS output for Homo sapiens SMC4 (a),
H. sapiens SMC2 (b), Xenopus laevi SMC4
(c), X. laevi SMC2 (d), fission yeast
(Schizosaccharomyces pombe) SMC4 (e), fission yeast
SMC2 (f), budding yeast (Saccharomyces cerevisiae)
SMC4 (g), and budding yeast SMC2 (h). The vertical
axis denotes the probability of the amino acid sequence adopting a
coiled-coil structure based on a scanning window of 28 residues.
Conserved disruptions in the coiled-coil structure prediction to the
condensin SMC sequences are indicated beneath the COILS
profile with an asterisk.