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. 1998 Dec;153(6):1937–1945. doi: 10.1016/S0002-9440(10)65707-0

Figure 8.

Figure 8.

Effects of CsA, FK-506, and EGTA on apoptosis induced by anti-CD99 MAb or calcium ionophore. RD-ES cells were preincubated with CsA or FK-506 for 2 hours before the induction of apoptosis by anti-CD99 MAb at 10 μg/ml (A) or calcium ionophore A23187 at 10 μmol/L (B). In the case of EGTA treatment, RD-ES cells were preincubated with a combination of 1.5 mmol/L EGTA and 1.5 mmol/L MgCl2 for 1 hour before the induction of apoptosis (C). Results are expressed as percentages of dead cells measured by trypan blue dye exclusion.