Table 2.

List of Web Services related to IARC TP53 Mutation Database.

Web Service Name	Input	Output
getP53MutationsByProperty	lib, text	Full record
getP53MutationsByIds	Id	Full record
getP53MutationIdsByType	lib, mutation type	id(s)
getP53MutationIdsByEffect	lib, effect	id(s)
getP53MutationIdsByExon	lib, exon number	id(s)
getP53MutationIdsByIntron	lib, intron number	id(s)
getP53MutationIdsByCodonNumber	lib, codon number	id(s)
getP53MutationIdsByCpgSite	lib, cpg site (true/false)	id(s)
getP53MutationIdsBySpliceSite	lib splice site (true/false)	id(s)
getP53MutationIdsByMetastasisLocalization	lib, metastasis localization (organ)	id(s)
getP53MutationIdsByTumorOrigin	lib, origin (primary, secondary, ...)	id(s)

This table lists all Web Services that have been created with the aim of allowing data retrieval from IARC TP53 Mutation Database. Here id refers to the Mutation_ID defined by IARC, while lib refers to the name of involved database that currently is 'tp53_iarc' but has been parameterized in view of future extension of the system, allowing the search of other databases as well.