Table 2.
Immunoreactivity of Ki-A10 in Germ Cell Tumors and Gonadal Stromal Tumors
| Parameters | Overall positive | Focally positive | Negative |
|---|---|---|---|
| Monotypic germ cell tumors | |||
| Seminoma [38] | 38 | 0 | 0 |
| Metastatic seminoma [7] | 7 | 0 | 0 |
| Dysgerminoma [9] | 9 | 0 | 0 |
| Gonadoblastoma [4] | 4 | 0 | 0 |
| Yolk sac tumor [29] | 7 | 9 | 13 |
| Choriocarcinoma [3] | 0 | 1 | 2 |
| Embryonal carcinoma [17] | 0 | 0 | 17 |
| Teratoma (mature) [12] | 1* | 0 | 11 |
| Teratoma (immature) [7] | 0 | 0 | 7 |
| Mixed germ cell tumors [45] (components) | |||
| Seminoma [17] | 17 | 0 | 0 |
| Dysgerminoma [11] | 11 | 0 | 0 |
| Yolk sac tumor [34] | 8 | 11 | 15 |
| Choriocarcinoma [6] | 0 | 2 | 4 |
| Embryonal carcinoma [26] | 0 | 0 | 26 |
| Teratoma (mature) [25] | 0 | 0 | 25 |
| Teratoma (immature) [10] | 0 | 0 | 10 |
| IGCN (all cases) [71] | 71 | 0 | 0 |
| Stromal tumors [18] | |||
| Sertoli cell tumor [7] | 0 | 0 | 7 |
| Leydig cell tumor [4] | 0 | 0 | 4 |
| Thecoma [4] | 0 | 0 | 4 |
| Granulosa cell tumor [3] | 0 | 0 | 3 |
Items in brackets indicate the numbers of cases.
*Positive immunoreaction confined to an undifferentiated gonad within a mature teratoma.