Table 3.
Summary of the Pathological Responses in Mongolian Gerbils of Hyperplastic Group Infected with H. pylori from 33 to 59 Weeks
| Age (weeks) | Length of coloni- zation (weeks) | No. of gerbils | Body weight (g) | Antibody titer (AI) | Fundic mucosa/ Total mucosa (%) | Antrum | Corpus | Poly | Mono | Number of intestinal metaplasia | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BrdU index | Proliferative zone thickness/Mucosal thickness (%) | Mucosal thickness (mm) | SMGL (mm) | BrdU index | Proliferative zone thickness/Mucosal thickness (%) | Mucosal thickness (mm) | SMGL (mm) | |||||||||
| 33 | 26 | 3 | 95.9 | 182.7 | 28.7 | 23 | 65 | 1.17 | 0.09 | 7 | 12 | 0.98 | 0.03 | 1.7 | 1.7 | 1.7 |
| 45 | 38 | 4 | 106.1 | 209.2 | 28 | 25 | 72 | 1.52 | 0.25 | 6 | 12 | 1.1 | 0.05 | 1.7 | 1.3 | 10.3 |
| 59 | 52 | 13 | 116.2 | 168.8 | 24.3 | 24 | 89 | 1.63 | 0.21 | 3 | 11 | 1.18 | 0.06 | 1.5 | 1.8 | 11.8 |
AI, arbitrary index; BrdU, 5′-bromo-2′deoxyuridine; Poly, polymorphonuclear neutrophil; Mono, mononuclear cell; SMGL, surface mucous gel layer.