Table 4.

Complement mRNAs in Various Tissues

mRNA	Hippocampus		Liver		Spleen		Kidney		Heart		AD Hipp/AD Liver
	AD	Control	AD	Control	AD	Control	AD	Control	AD	Control
C1q	79.5 ± 9.0	3.45 ± 1.5	18.1 ± 1.6	15.9 ± 3.2	2.9 ± 2.4	1.8 ± 0.6	4.6 ± 3.5	2.1 ± 0.9	1.1 ± 1.1	0.7 ± 0.7	4.39
C1r	59.7 ± 6.3	12.9 ± 3.6	28.2 ± 2.7	30.8 ± 0.7	18.7 ± 6.3	18.6 ± 1.8	21.1 ± 2.0	15.3 ± 2.2	11.0 ± 4.0	8.4 ± 3.2	2.11
C1s	58.0 ± 3.1	19.3 ± 5.3	37.5 ± 5.3	46.0 ± 3.1	19.2 ± 5.1	23.5 ± 1.7	22.0 ± 0.7	19.3 ± 1.4	11.2 ± 4.5	9.2 ± 4.8	1.55
C2	37.7 ± 4.1	24.1 ± 1.7	10.3 ± 6.4	16.3 ± 2.3	17.6 ± 2.5	17.8 ± 2.0	20.6 ± 4.8	15.5 ± 1.6	10.3 ± 6.1	8.1 ± 4.2	3.74
C3	141 ± 14	73.1 ± 1.9	72.9 ± 8.1	74.6 ± 4.1	58.0 ± 4.8	56.1 ± 3.7	53.4 ± 7.6	53.3 ± 2.3	34.8 ± 6.3	29.1 ± 5.7	1.93
C4	141 ± 3	74.9 ± 1.4	72.5 ± 5.8	76.6 ± 1.5	52.1 ± 5.2	53.6 ± 3.0	52.6 ± 7.8	50.3 ± 2.8	25.4 ± 5.5	30.3 ± 7.0	1.94
C5	36.7 ± 7.7	20.2 ± 0.1	17.2 ± 2.8	16.0 ± 2.5	13.2 ± 3.6	12.7 ± 1.1	11.1 ± 3.8	14.4 ± 2.3	8.4 ± 5.0	5.1 ± 1.9	2.13
C6	28.9 ± 1.6	15.5 ± 2.4	24.9 ± 5.5	17.3 ± 1.8	7.2 ± 1.6	7.9 ± 1.5	6.3 ± 1.1	3.4 ± 1.0	1.7 ± 1.7	0.8 ± 0.7	1.16
C7	39.8 ± 3.6	6.3 ± 4.1	27.3 ± 1.4	35.7 ± 3.4	15.0 ± 3.8	13.4 ± 2.5	14.7 ± 3.9	14.5 ± 2.1	4.1 ± 0.8	4.7 ± 0.6	1.46
C8	42.6 ± 2.9	15.3 ± 8.0	28.7 ± 8.2	41.0 ± 3.9	3.6 ± 2.1	1.5 ± 0.7	3.3 ± 1.7	1.8 ± 0.9	6.5 ± 6.5	0 ± 0	1.48
C9	56.4 ± 8.0	2.55 ± 0.8	23.2 ± 7.6	27.6 ± 2.4	3.9 ± 2.8	1.3 ± 0.7	3.2 ± 1.7	2.6 ± 0.8	3.6 ± 2.6	0.5 ± 0.5	2.43
Cyc/100	85.4 ± 1.1	85.5 ± 1.8	94.6 ± 0.9	94.8 ± 0.8	107 ± 0.9	108 ± 1	94.5 ± 0.5	93.8 ± 0.8	94.3 ± 1.7	94.1 ± 1.6	0.90
N	4	5	3	10	3	11	3	11	3	4

Data are means ± S.E., with N for each tissue indicated in the bottom line. In no case was there a significant difference by ANOVA between the AD and control data except in the hippocampus as indicated in Figure 2 ▶ .