Table 4.
Cellular Infiltration into Lungs of Wild-type, μMT, and SCID Mice Treated with Anti-CD40 mAb
| Mice | Antibody treatment | Total macrophages (×106) | Total lymphocytes (×106) | Total PMN (×106) |
|---|---|---|---|---|
| +/+ | Anti-CD40 | 1.80 ± 0.73 | 5.36 ± 2.46 | 1.37 ± 0.52 |
| μMT | Anti-CD40 | 1.02 ± 0.48 | 3.81 ± 1.83 | 3.79 ± 1.34* |
| SCID | Anti-CD40 | 0.85 ± 0.54* | 0.16 ± 0.07* | 1.99 ± 0.91 |
Measurements are means ± SD, n = 7 to 8 mice/group.
*Statistically significant differences were observed relative to the +/+ mice, P < 0.05.