Table 2.
Correlation Coefficients (ρ) between Expression Frequencies of the Related Proteins in Tumor Cells
| Cyclin A | Cdk2 | CAK | P21 | p27 | p53 | |
|---|---|---|---|---|---|---|
| Cyclin A | — | 0.74** | 0.12 | 0.078 | 0.312 | N.D. |
| Cdk2 | 0.74** | — | 0.11 | 0.089 | 0.53* | N.D. |
| CAK | 0.12 | 0.11 | — | N.D. | N.D. | N.D. |
| P21 | 0.078 | 0.089 | N.D. | — | −0.573** | −0.171 |
| p27 | 0.312 | 0.53* | N.D. | −0.573** | — | N.D. |
| p53 | N.D. | N.D. | N.D. | −0.171 | N.D. | — |
*P < 0.01
**P < 0.001.
CAK, cdk-activating kinase; N.D., not determined.
Positive ratios of the tumor cells on immunohistochemical staining against respective proteins counted in the peripheral region of the tumor nodule in each case were analyzed by Spearman’s rank test.