Table 1.
Two-point LOD scores for maximum number of cigarettes per day.A
Parametric AnalysisD | Variance Components Analysis | |||||||
ChrB | cMC | Marker | Un- adjusted (θ) | Sex, age adjusted (θ) | Sex, age, year adjusted (θ) | Un- adjusted | Sex, age adjusted | Sex, age, year adjusted |
1 | 167.15 | GATA12A07 | 0.54 (0.3) | 0.21 (0.3) | 0.37 (0.3) | 1.28 | 0.89 | 0.44 |
1 | 187.86 | GGAA5F09 | 0.57 (0.3) | 0.21 (0.3) | 0.75 (0.3) | 1.46 | 1.34 | 0.82 |
1 | 193.02 | GGAA22G10 | 0.90 (0.3) | 0.44 (0.3) | 0.57 (0.3) | 1.13 | 0.94 | 0.54 |
2 | 70.32 | ATA4F03 | 1.98 (0.2) | 1.61 (0.2) | 0.80 (0.3) | 0.04 | 0.07 | 0.01 |
2 | 100.60 | GATA69E12 | 0.75 (0.3) | 0.68 (0.3) | 0.69 (0.3) | 0.55 | 1.02 | 0.99 |
2 | 237.47 | GATA4G12 | 0.03 (0.4) | 0.00 | 0.00 | 0.99 | 1.09 | 0.71 |
7 | 62.68 | GATA31A10 | 0.08 (0.4) | 0.00 | 0.00 | 1.10 | 0.80 | 0.64 |
8 | 24.63 | GATA25C10 | 0.05 (0.4) | 0.06 (0.4) | 0.02 (0.4) | 0.45 | 0.74 | 1.04 |
11 | 58.51 | ATA1B07 | 0.84 (0.1) | 0.74 (0.1) | 0.60 (0.2) | 0.81 | 1.10 | 0.97 |
12 | 53.27 | ATA27A06 | 0.00 | 0.09 (0.4) | 0.09 (0.4) | 0.20 | 0.88 | 1.12 |
13 | 83.74 | GATA43H03 | 0.00 | 0.01 (0.4) | 0.58 (0.3) | 0.54 | 0.64 | 1.06 |
15 | 65.52 | GATA151F03 | 0.83 (0.3) | 1.09 (0.2) | 0.67 (0.3) | 0.49 | 0.21 | 0.02 |
17 | 66.85 | GATA25A04 | 1.52 (0.2) | 1.39 (0.2) | 0.77 (0.3) | 0.81 | 0.69 | 0.19 |
17 | 138.03 | 217yd10 | 0.05 (0.4) | 0.12 (0.4) | 0.08 (0.4) | 1.12 | 1.35 | 1.08 |
20 | 70.51 | GATA47F05 | 0.82 (0.3) | 1.30 (0.2) | 1.19 (0.3) | 0.36 | 1.07 | 1.39 |
20 | 84.62 | 321xd1 | 0.61 (0.2) | 1.02 (0.2) | 1.24 (0.2) | 0.77 | 0.95 | 0.98 |
AMarkers shown have a LOD = 1. Bold, LOD > 1. BChr, chromosome. CcM, sex-averaged distance from p-term. DParametric LODs are maximized over θ.