Table 2.
Estimates of heritabilities, genetic and residual correlations between traits from Cohorts 1 and 2
| Cohort 2 | Cohort 1 | ||||||
| Alcohol | Cholesterol | Glucose | Triglyceride | Alcohol | Glucose | Triglyceride | |
| Cohort 2 | |||||||
| AlcoholA | 0.05 (0.02)B | 0.26 (0.08) | -0.20 (0.10) | 0.25 (0.08) | 0.10 (0.08) | -0.06 (0.25) | 0.01 (0.09) |
| Cholesterol | -0.10 (0.04) | 0.71 (0.04) | 0.06 (0.02) | 0.15 (0.02) | -0.19 (0.13) | 0.07 (0.03) | 0.07 (0.03) |
| Glucose | 0.00 (0.03) | -0.04 (0.04) | 0.62 (0.03) | 0.48 (0.04) | 0.12 (0.16) | 0.98 (0.02) | 0.52 (0.04) |
| Triglyceride | 0.55 (0.02) | 0.03 (0.03) | 0.26 (0.04) | 0.40 (0.03) | -0.48 (0.22) | 0.58 (0.04) | 0.94 (0.04) |
| Cohort 1 | |||||||
| Alcohol | 0C | 0 | 0 | 0 | 0.04 (0.02) | 0.01 (0.18) | -0.65 (0.16) |
| Glucose | 0 | 0 | 0 | 0 | 0.04 (0.05) | 0.65 (0.02) | 0.62 (0.04) |
| Triglyceride | 0 | 0 | 0 | 0 | 0.56 (0.03) | -0.12 (0.07) | 0.64 (0.02) |
AThese are the 1st PCA of the traits described in Table 1, except for TG in Cohort 1, which is the original measurement; see text for details. BHeritabilities (in bold) are on the diagonal, genetic correlations are above and residual correlations are below the diagonal. All parameters have their standard errors in parentheses. The multivariate mixed model implemented for the parameter estimates used traits across cohorts. CThe residual correlation between the two cohorts is equal to 0 by definition with the model fitted here.