Histologic appearance of type-2 lung granulomas in wild type and CCR2 knockout mice. A, B, and C: Lesions of wild type mice on days 2, 4 and 8 respectively. D, E, and F: Lesions of knockout mice on days 2, 4, and 8, respectively. Day 2 knockout lesions contained fewer mononuclear cells. Hematoxylin and eosin stain. Magnification, ×200.